Founded in 1749 by Sephardic immigrants, KKBE is the oldest continuously used synagogue in the United States and a cornerstone of American Jewish history. Its 1840 sanctuary is the birthplace of Reform Judaism in the U.S., where congregants began advocating for changes such as the inclusion of women in religious services.

Founded in the mid-19th century, BSBI is the oldest Orthodox Ashkenazi synagogue in continuous use in the United States. It remained active during the Civil War and represents the arrival of Central and Eastern European Jews who helped sustain traditional Jewish practice in Charleston.

Established in 1764, this sacred site is the oldest surviving Jewish cemetery in the South. It contains the graves of prominent Jewish Charlestonians, including Revolutionary War veterans, rabbis, and civic leaders — a quiet but powerful record of centuries of Jewish life.

Dr. Jacob de la Motta operated the first Jewish-owned pharmacy in the United States, located in what is believed to be the oldest surviving structure in Charleston. The site reflects both his pioneering role in American medicine and the early presence of Jewish professionals in the city.

Grace Peixotto, the daughter of a prominent Jewish family, ran Charleston’s most infamous brothel in the 19th century. Her story offers a provocative lens on gender, class, and Jewish identity in the antebellum South.

Abraham Sasportas, a French-born Jewish merchant, lived in this house during the American Revolution. A supporter of the patriot cause, he played a crucial role in privateering operations against the British, reflecting the civic engagement of Charleston’s early Jewish residents.

Built in 1802, the Hebrew Orphan Society is the oldest chartered Jewish charity in the United States. It reflects the long-standing tradition of philanthropy and mutual aid within Charleston’s Jewish community.

The Pollitzer House was home to one of Charleston’s prominent Jewish families, whose daughters—Carrie, Mabel, and Anita—became influential advocates for women’s rights and education. Their legacy connects Charleston’s Jewish community to major national reform movements of the early 20th century.

Isaac Harby, a journalist, playwright, and pioneering advocate for religious reform, lived in this modest home in the early 19th century, where he also ran a small school. A key founder of Reform Judaism in America, Harby helped establish Charleston as a center of Jewish intellectual and religious innovation.

Moses Cohen Mordecai, a wealthy Jewish shipping magnate and newspaper publisher, lived in this grand antebellum home. Initially a vocal opponent of secession through his paper The Southern Standard, he later became a supporter of the Confederacy - embodying the internal conflicts faced by Southern Jews during the Civil War.

“Little Jerusalem” was the heart of Jewish life in 19th-century Charleston. The neighborhood included synagogues, kosher butchers, Hebrew schools, and family-run businesses, and remains one of the most historically significant Jewish enclaves in the American South.

Located in Marion Square, Charleston’s Holocaust Memorial honors the memory of the six million Jews murdered during the Holocaust. It also serves as a public space for reflection and a commitment to remembrance, education, and tolerance.